Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21694917 | 0.88 | KDM4E (0.49) | KDM4EL3MBTL1MAPT | |
| SCHEMBL5148049 | 0.87 | KDM4E (0.60) | KDM4EL3MBTL1MAPT | |
| SCHEMBL19601301 | 0.83 | ABCB1 (0.35) | KDM4EL3MBTL1 | |
| SCHEMBL9003278 | 0.83 | KDM4E (0.52) | KDM4EL3MBTL1MAPT | |
| SCHEMBL79622 | 0.82 | TSHR (0.37) | KDM4EL3MBTL1 | |
| SCHEMBL9003514 | 0.81 | KDM4E (0.50) | KDM4EL3MBTL1MAPT | |
| SCHEMBL17223623 | 0.81 | KDM4E (0.55) | KDM4EL3MBTL1MAPT | |
| SCHEMBL17383350 | 0.81 | KDM4E (0.34) | KDM4EL3MBTL1 | |
| SCHEMBL20356793 | 0.81 | CA12 (0.46) | KDM4EL3MBTL1MAPT | |
| SCHEMBL17223961 | 0.79 | KDM4E (0.49) | KDM4EL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182203-B1 | DELAYED ACTION/ENHANCED CURING CATALYSIS IN POLYURETHANE SYSTEMS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-08-12 | — | — | EP | claimed |
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |
| CN-106398581-B | Antistatic agent for adhesive | 第一工业制药株式会社 | 2020-06-23 | — | — | CN | disclosed |
| US-10005743-B2 | Methods for producing viloxazine salts and novel polymorphs thereof | SUPERNUS PHARMACEUTICALS, INC. (US) | 2018-06-26 | — | — | US | disclosed |
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-11-16 | — | — | US | disclosed |
| EP-3205652-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2017-08-16 | — | — | EP | disclosed |
| US-20160304475-A1 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | SUPERNUS PHARMACEUTICALS, INC. (US) | 2016-10-20 | — | — | US | disclosed |
| US-9434703-B2 | Viloxazine compositions | SUPERNUS PHARMACEUTICALS, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9403783-B2 | Methods for producing viloxazine salts and novel polymorphs thereof | SUPERNUS PHARMACEUTICALS, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150126735-A1 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | SUPERNUS PHARMACEUTICALS INC. (US) | 2015-05-07 | — | — | US | disclosed |
| US-8361779-B2 | Buffer compounds | SACHEM, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120129240-A1 | BUFFER COMPOUNDS | SACHEM, INC. | 2012-05-24 | — | — | US | disclosed |
| US-20110251198-A1 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | SUPERNUS PHARMACEUTICALS INC. (US) | 2011-10-13 | — | — | US | disclosed |
| EP-1171558-A1 | SOFTENER COMPOSITIONS HAVING HIGH HYDROLYTIC STABILITY AND CONCENTRATIBILITY | THE DOW CHEMICAL COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-1102833-A1 | COMPOSITION USEFUL FOR SOFTENING, CLEANING, AND PERSONAL CARE APPLICATIONS | THE DOW CHEMICAL COMPANY (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000058427-A1 | SOFTENER COMPOSITIONS HAVING HIGH HYDROLYTIC STABILITY CONCENTRATIBILITY | THE DOW CHEMICAL COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000006678-A1 | COMPOSITION USEFUL FOR SOFTENING, CLEANING, AND PERSONAL CARE APPLICATIONS | THE DOW CHEMICAL COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005743-B2 | Methods for producing viloxazine salts and novel polymorphs thereof | CYP3A5, VIL1, CYP3A4 | KDM4E 1827/4885L3MBTL1 2057/4885MAPT 3092/4885 |
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | PNP, PDE2A, PDE7A | KDM4E 4302/4885L3MBTL1 4846/4885MAPT 974/4885 |
| US-20160304475-A1 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | CYP3A5, VIL1, CYP3A4 | KDM4E 1827/4885L3MBTL1 2057/4885MAPT 3092/4885 |
| US-20150126735-A1 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | CYP3A5, VIL1, CYP3A4 | KDM4E 1827/4885L3MBTL1 2057/4885MAPT 3092/4885 |
| US-20110251198-A1 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | CYP3A5, VIL1, CYP3A4 | KDM4E 1827/4885L3MBTL1 2057/4885MAPT 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.