⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319456 | 0.69 | — | — | |
| SCHEMBL18887352 | 0.69 | — | — | |
| SCHEMBL15059285 | 0.69 | — | — | |
| SCHEMBL8676820 | 0.67 | — | — | |
| SCHEMBL28019134 | 0.65 | — | — | |
| SCHEMBL21736991 | 0.65 | — | — | |
| SCHEMBL25422886 | 0.65 | — | — | |
| SCHEMBL20501247 | 0.65 | — | — | |
| SCHEMBL20844222 | 0.65 | — | — | |
| SCHEMBL12778094 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425649-A | Pyrazole derivatives as KRAS mutein inhibitors | 诺华股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| WO-2023169456-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| CN-114945366-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114929342-A | Pyrazolyl derivatives as anticancer agents | 诺华股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2021120890-A1 | PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-06-24 | — | — | WO | disclosed |
| CN-106458994-B | Biaryl kinase inhibitor | 百时美施贵宝公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-104725384-B | MTOR kinase inhibitor for tumour indication relevant to mTOR/PI3K/AKT/ approach and disease | 西格诺药品有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-109970708-A | Cannibinoid receptor modulators | 艾尼纳制药公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-104926801-B | Substituted azetidine analog derivative, the pharmaceutical composition containing it and its application in antitumor | 浙江大学 | 2019-06-04 | — | — | CN | disclosed |
| CN-103492369-B | Cannabinoid receptor modulators | 艾尼纳制药公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-108368084-A | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108024992-A | Aryl, Heteroaryl and Heterocyclic Compounds for the Treatment of Medical Disorders | 艾其林医药公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-104744475-B | MTOR kinase inhibitors for the tumour indication and disease related to mTOR/PI3K/AKT/ approach | 西格诺药品有限公司 | 2018-01-12 | — | — | CN | disclosed |
| WO-2017097234-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-06-15 | — | — | WO | disclosed |
| CN-103221412-B | (aza) indolizine derivatives and their pharmaceutical use | Kissei Pharmaceutical Co.,Ltd. (JP) | 2015-08-19 | — | — | CN | disclosed |
| CN-104592224-A | (AZA)INDOLIZINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | KISSEI PHARMACEUTICAL | 2015-05-06 | — | — | CN | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |