Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507665 | 0.88 | CA1 (0.54) | ALDH1A1THRBATMCA1CA2 | |
| SCHEMBL6045338 | 0.82 | KCNN4 (0.55) | ALDH1A1CA1CA2MAPT | |
| Anisaldehyde SCHEMBL28156946 | 0.82 | ALDH1A1 (0.79) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL9090048 | 0.82 | ALDH1A1 (0.79) | ALDH1A1CYP2A6THRBATMF3 | |
| SCHEMBL13701346 | 0.81 | ALDH1A1 (0.70) | ALDH1A1CYP2A6THRBATMF3 | |
| SCHEMBL19214411 | 0.80 | ALDH1A1 (0.76) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL18227043 | 0.80 | ALDH1A1 (0.83) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL2239445 | 0.80 | ALDH1A1 (0.91) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL717471 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL1100 | 0.80 | ALDH1A1 (1.00) | ALDH1A1CYP2A6THRBATMF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318699-B2 | Tumor necrosis factor inhibitors | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-11-27 | — | — | US | disclosed |
| US-20090221527-A1 | TUMOR NECROSIS FACTOR INHIBITORS | CEPTION THERAPEUTICS, INC. (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221527-A1 | TUMOR NECROSIS FACTOR INHIBITORS | TNFRSF1A, TNF, TNFRSF9 | ALDH1A1 3912/4885CYP2A6 4354/4885THRB 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.