Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.76 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisaldehyde SCHEMBL717471 | 0.87 | ALDH1A1 (1.00) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| Anisaldehyde SCHEMBL1100 | 0.87 | ALDH1A1 (1.00) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| SCHEMBL5604880 | 0.86 | ALDH1A1 (0.73) | ALDH1A1CYP2A6TYRALDH1A3TSHR | |
| Anisaldehyde SCHEMBL31123393 | 0.85 | ALDH1A1 (0.95) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| Anisaldehyde SCHEMBL11255570 | 0.85 | ALDH1A1 (0.95) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| Anisaldehyde SCHEMBL1475478 | 0.85 | ALDH1A1 (0.95) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| Anisaldehyde SCHEMBL28556480 | 0.85 | ALDH1A1 (0.95) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| Anisaldehyde SCHEMBL1477047 | 0.85 | ALDH1A1 (0.95) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| Anisaldehyde SCHEMBL28973891 | 0.85 | ALDH1A1 (0.95) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR | |
| Anisaldehyde SCHEMBL28776745 | 0.85 | ALDH1A1 (0.95) | ALDH1A1CYP2A6ALDH1A3GSK3BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318699-B2 | Tumor necrosis factor inhibitors | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-11-27 | — | — | US | disclosed |
| US-20090221527-A1 | TUMOR NECROSIS FACTOR INHIBITORS | CEPTION THERAPEUTICS, INC. (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221527-A1 | TUMOR NECROSIS FACTOR INHIBITORS | TNFRSF1A, TNF, TNFRSF9 | ALDH1A1 3912/4885CYP2A6 4354/4885SLC2A1 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.