⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741689 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL2774537 | 0.65 | ALDH1A1 (0.34) | — | |
| SCHEMBL6364804 | 0.62 | — | — | |
| SCHEMBL13892882 | 0.60 | — | — | |
| SCHEMBL20080617 | 0.59 | — | — | |
| SCHEMBL3841158 | 0.57 | — | — | |
| SCHEMBL379946 | 0.55 | — | — | |
| SCHEMBL11773518 | 0.55 | — | — | |
| SCHEMBL11775307 | 0.55 | — | — | |
| SCHEMBL1856253 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585622-B1 | Increasing the proliferative capacity of cells using telomerase reverse transcriptase | GERON CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |