Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13229125 | 0.83 | KMT2A (0.90) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL13701737 | 0.83 | KMT2A (0.74) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL1696458 | 0.82 | KMT2A (0.77) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL15676710 | 0.81 | KMT2A (0.82) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL13702339 | 0.81 | SMN1; SMN2 (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC6 | |
| SCHEMBL13229122 | 0.81 | KMT2A (0.80) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL13702290 | 0.80 | HDAC6 (0.74) | KMT2AALDH1A1SMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL1003665 | 0.79 | KMT2A (0.83) | KMT2AMEN1ALDH1A1HDAC1HDAC6 | |
| SCHEMBL9713054 | 0.79 | SMN1; SMN2 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL18186542 | 0.79 | KMT2A (0.82) | KMT2AMEN1ALDH1A1SMN1; SMN2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | KMT2A 3792/4885MEN1 4409/4885ALDH1A1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.