Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 0.86 |
| ▸ | CA12 | O43570 | 2/20 | 0.77 |
| ▸ | CA1 | P00915 | 2/20 | 0.77 |
| ▸ | CA2 | P00918 | 2/20 | 0.77 |
| ▸ | CA4 | P22748 | 2/20 | 0.77 |
| ▸ | CA9 | Q16790 | 2/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.70 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.70 |
| ▸ | FABP2 | P12104 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669346 | 0.92 | LMNA (0.86) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5350115 | 0.91 | LMNA (0.84) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5350109 | 0.91 | LMNA (0.84) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5325984 | 0.90 | LMNA (0.82) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL13704192 | 0.90 | LMNA (0.82) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5325980 | 0.90 | LMNA (0.82) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL28689425 | 0.89 | LMNA (0.80) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5321570 | 0.89 | LMNA (0.80) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5321562 | 0.89 | LMNA (0.80) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30536489 | 0.89 | LMNA (0.80) | LMNASMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585997-B2 | Compounds and compositions for treating dysproliferative diseases, and methods of use thereof | CHESTERFORD ENTERPRISES LIMITED (KY) | 2009-09-08 | — | — | US | disclosed |
| US-7585997-B2 | Compounds and compositions for treating dysproliferative diseases, and methods of use thereof | CHESTERFORD ENTERPRISES LIMITED (KY) | 2009-09-08 | — | — | US | disclosed |