Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | USP19 | O94966 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810259 | 0.88 | ACP1 (0.34) | USP19HCRTR1HCRTR2CHRNA7KCNH2 | |
| SCHEMBL13705410 | 0.88 | CA1 (0.33) | USP19HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL13705452 | 0.88 | HCRTR1 (0.38) | USP19HCRTR1HCRTR2CHRNA7KCNH2 | |
| SCHEMBL13705403 | 0.87 | CHRM3 (0.34) | USP19HCRTR1HCRTR2CHRNA7KCNH2 | |
| SCHEMBL13705466 | 0.87 | HCRTR1 (0.41) | USP19HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL4281603 | 0.85 | ACP1 (0.35) | USP19HCRTR1HCRTR2CHRNA7KCNH2 | |
| SCHEMBL13705473 | 0.85 | HCRTR1 (0.40) | USP19HCRTR1HCRTR2CHRM3 | |
| SCHEMBL4292457 | 0.85 | HCRTR1 (0.39) | USP19HCRTR1HCRTR2CHRNA7KCNH2 | |
| SCHEMBL13705478 | 0.84 | HCRTR1 (0.44) | ALDH1A1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL13705419 | 0.84 | HCRTR1 (0.40) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885HPGD 106/4885APOBEC3A 4376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.