Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580128 | 0.78 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL3584432 | 0.72 | MTNR1A (0.67) | MTNR1AMTNR1BHTT | |
| SCHEMBL3581903 | 0.72 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3582414 | 0.71 | MTNR1A (0.65) | MTNR1AMTNR1BHTT | |
| SCHEMBL3583501 | 0.69 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL3574649 | 0.68 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL11985466 | 0.68 | MTNR1A (0.41) | MTNR1AMTNR1B | |
| SCHEMBL3578336 | 0.68 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3575806 | 0.67 | MTNR1A (0.41) | MTNR1AMTNR1B | |
| SCHEMBL13705665 | 0.67 | MTNR1A (0.79) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098513-A1 | TRICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-09-09 | — | — | EP | disclosed |