Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.53 |
| ▸ | PRF1 | P14222 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16532888 | 0.97 | PGR (0.51) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL20043837 | 0.97 | PGR (0.51) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL18032747 | 0.87 | PGR (0.44) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL20043828 | 0.83 | PGR (0.41) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL2394968 | 0.82 | APP (0.48) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL14666145 | 0.80 | APP (0.41) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL13931311 | 0.80 | APP (0.58) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL18546224 | 0.78 | PRF1 (0.65) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL15592649 | 0.77 | PRF1 (0.43) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL13705997 | 0.76 | PGR (0.34) | PGRPRF1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589166-B2 | Thiophene-containing compound and polymer thereof | FUJI XEROX CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |