Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN4 | Q9Y3Q4 | 4/20 | 0.51 |
| ▸ | HCN1 | O60741 | 3/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 9/20 | 0.44 |
| ▸ | IL1B | P01584 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706846 | 0.92 | HCN4 (0.59) | HCN4HCN1P2RX7SLC6A9IL1B | |
| SCHEMBL4530146 | 0.92 | HCN4 (0.54) | HCN4HCN1P2RX7SLC6A9IL1B | |
| SCHEMBL4537218 | 0.92 | HCN4 (0.54) | HCN4HCN1P2RX7SLC6A9IL1B | |
| SCHEMBL13706839 | 0.90 | HCN4 (0.52) | HCN4HCN1P2RX7SLC6A9IL1B | |
| SCHEMBL4351646 | 0.89 | P2RX7 (0.49) | HCN4HCN1P2RX7SLC6A9IL1B | |
| SCHEMBL4537785 | 0.86 | HCN4 (0.52) | HCN4HCN1P2RX7SLC6A9IL1B | |
| SCHEMBL4353725 | 0.85 | HCN4 (0.54) | HCN4HCN1P2RX7SLC6A9 | |
| SCHEMBL4538239 | 0.85 | P2RX7 (0.46) | HCN4HCN1P2RX7IL1B | |
| SCHEMBL4523000 | 0.85 | P2RX7 (0.46) | HCN4HCN1P2RX7IL1B | |
| SCHEMBL4531474 | 0.85 | P2RX7 (0.47) | HCN4P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |