Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13707916 | 1.00 | MAPK1 (0.42) | MAPK1GRNSORT1CTSKTSHR | |
| SCHEMBL27437691 | 0.83 | MAPK1 (0.43) | MAPK1GRNSORT1CTSK | |
| SCHEMBL19546255 | 0.83 | MAPK1 (0.43) | MAPK1GRNSORT1CTSK | |
| SCHEMBL13711068 | 0.81 | MAPK1 (0.40) | MAPK1GRNSORT1 | |
| SCHEMBL13711120 | 0.81 | MAPK1 (0.40) | MAPK1GRNSORT1 | |
| SCHEMBL25453637 | 0.80 | MAPK1 (0.41) | MAPK1GRNSORT1CTSKCYP3A4 | |
| SCHEMBL23177702 | 0.79 | ECE1 (0.33) | — | |
| SCHEMBL4682422 | 0.78 | GRN (0.43) | MAPK1GRNSORT1CTSKTSHR | |
| SCHEMBL13707883 | 0.75 | CYP2D6 (0.43) | CTSK | |
| SCHEMBL13707892 | 0.75 | CYP2D6 (0.43) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595299-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| US-7169760-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |