Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NPR3 | P17342 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19546255 | 1.00 | MAPK1 (0.43) | MAPK1GRNSORT1CTSKNPR3 | |
| SCHEMBL13707884 | 0.83 | MAPK1 (0.42) | MAPK1GRNSORT1CTSK | |
| SCHEMBL13707916 | 0.83 | MAPK1 (0.42) | MAPK1GRNSORT1CTSK | |
| SCHEMBL25453637 | 0.81 | MAPK1 (0.41) | MAPK1GRNSORT1CTSKNPR3 | |
| SCHEMBL13166785 | 0.81 | MAPK1 (0.39) | MAPK1GRNSORT1 | |
| SCHEMBL27420062 | 0.81 | MAPK1 (0.39) | MAPK1GRNSORT1 | |
| SCHEMBL20850028 | 0.81 | MAPK1 (0.39) | MAPK1GRNSORT1 | |
| SCHEMBL19318581 | 0.78 | GRN (0.39) | MAPK1GRNSORT1CTSK | |
| SCHEMBL19318538 | 0.78 | GRN (0.39) | MAPK1GRNSORT1CTSK | |
| SCHEMBL18594672 | 0.78 | TGFBR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216526-A1 | PREPARATION METHOD FOR DUAL-DRUG-LINKER OF ADC AND USE THEREOF | CHENGDU SCIMOUNT PHARMATECH CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216526-A1 | PREPARATION METHOD FOR DUAL-DRUG-LINKER OF ADC AND USE THEREOF | SKP1, ADCY7, ERBB2 | MAPK1 822/4885GRN 4701/4885SORT1 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.