Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | DVL1 | O14640 | 1/20 | 0.37 |
| ▸ | DVL3 | Q92997 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708909 | 0.86 | LMNA (0.44) | LMNASMO | |
| SCHEMBL10314246 | 0.82 | SMO (0.52) | LMNAHTR4SMO | |
| Hydrochloric Acid SCHEMBL1063285 | 0.82 | SMO (0.52) | LMNAHTR4SMO | |
| SCHEMBL12826058 | 0.79 | SMO (0.45) | HTR4SMODVL1DVL3 | |
| SCHEMBL13708904 | 0.78 | SMO (0.64) | LMNASMO | |
| SCHEMBL12826280 | 0.77 | SMO (0.43) | HTR4SMO | |
| SCHEMBL10314247 | 0.77 | SMO (0.55) | LMNASMO | |
| Hydrochloric Acid SCHEMBL1058628 | 0.76 | SMO (0.55) | LMNASMO | |
| SCHEMBL10314248 | 0.74 | SMO (0.64) | HTR4SMO | |
| Hydrochloric Acid SCHEMBL1060009 | 0.74 | SMO (0.63) | HTR4SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |