Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747719 | 0.91 | FAAH (0.41) | FAAHCYP3A4 | |
| SCHEMBL749340 | 0.85 | CYP3A4 (0.36) | FAAHCYP3A4 | |
| SCHEMBL12037742 | 0.84 | CYP3A4 (0.43) | FAAHCYP3A4 | |
| SCHEMBL762383 | 0.82 | FAAH (0.42) | FAAHCYP3A4 | |
| SCHEMBL746072 | 0.82 | FAAH (0.42) | FAAHCYP3A4 | |
| SCHEMBL16523929 | 0.82 | FAAH (0.42) | FAAHCYP3A4 | |
| SCHEMBL748558 | 0.80 | CYP3A4 (0.41) | FAAHCYP3A4 | |
| SCHEMBL744666 | 0.79 | CYP3A4 (0.44) | CYP3A4 | |
| SCHEMBL747191 | 0.79 | CYP3A4 (0.39) | FAAHCYP3A4 | |
| SCHEMBL16523944 | 0.79 | CYP3A4 (0.39) | FAAHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585862-B2 | Colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss | CHOONGWAE PHARMA CORPORATION (KR) | 2009-09-08 | — | — | US | disclosed |
| US-7585862-B2 | Colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss | CHOONGWAE PHARMA CORPORATION (KR) | 2009-09-08 | — | — | US | disclosed |