Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312507 | 0.91 | FFAR1 (0.44) | FFAR1FFAR4PTGER4PTGER2CYP4F2 | |
| SCHEMBL13312440 | 0.85 | FFAR1 (0.44) | FFAR1FFAR4PTGER4PTGER2CYP11B2 | |
| SCHEMBL13312504 | 0.82 | FFAR1 (0.48) | FFAR1FFAR4PTGER4PTGER2MAPK1 | |
| SCHEMBL13312511 | 0.79 | RXRA (0.42) | FFAR1FFAR4PTGER4PTGER2 | |
| SCHEMBL13312434 | 0.75 | FFAR1 (0.48) | FFAR1FFAR4PTGER4PTGER2 | |
| SCHEMBL13312452 | 0.74 | FFAR1 (0.45) | FFAR1FFAR4PTGER4PTGER2 | |
| SCHEMBL13312510 | 0.74 | FFAR4 (0.48) | FFAR1FFAR4PTGER4PTGER2NPC1 | |
| SCHEMBL13312441 | 0.74 | FFAR1 (0.43) | FFAR1FFAR4PTGER4PTGER2CYP4F2 | |
| SCHEMBL13312502 | 0.74 | FFAR1 (0.49) | FFAR1FFAR4PTGER4PTGER2 | |
| SCHEMBL13312443 | 0.74 | FFAR1 (0.43) | FFAR1FFAR4PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |