Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CALML3 | P27482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711511 | 0.92 | MAOA (0.48) | MAOACYP3A4CYP2D6CYP2C9CALML3 | |
| SCHEMBL13711519 | 0.92 | MAOA (0.47) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13711514 | 0.91 | MAOA (0.47) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13711631 | 0.90 | MAOA (0.48) | MAOACYP3A4CYP2D6CYP2C9CALML3 | |
| SCHEMBL13711512 | 0.88 | MAOA (0.42) | MAOACYP3A4CYP2C9CALML3 | |
| SCHEMBL13711577 | 0.87 | MAOA (0.45) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13711576 | 0.86 | MAOA (0.47) | MAOACYP3A4CYP2D6CYP2C9CALML3 | |
| SCHEMBL13711617 | 0.86 | MAOA (0.44) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3366625 | 0.86 | MAOA (0.68) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14012599 | 0.86 | MAOA (0.68) | MAOACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582659-B2 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO., INC. (US) | 2009-09-01 | — | — | US | disclosed |