Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12789745 | 0.88 | PNP (0.48) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL14393415 | 0.87 | ADORA2A (0.57) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL10457730 | 0.87 | ADORA2A (0.57) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL10458535 | 0.87 | ADORA2A (0.57) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL10456428 | 0.87 | ADORA2A (0.57) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL14393438 | 0.87 | ADORA2A (0.57) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL1244542 | 0.87 | ADORA2A (0.57) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL10458382 | 0.84 | ADORA3 (0.54) | ADORA1ADORA3 | |
| SCHEMBL12467509 | 0.82 | ADORA3 (0.55) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL12568399 | 0.81 | ADORA2A (0.59) | ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589076-B2 | Substituted aryl piperidinylalkynyladenosines as A2AR agonists | PGX HEALTH, LLC (US) | 2009-09-15 | — | — | US | disclosed |