Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327084 | 0.77 | HRH3 (0.41) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL28866503 | 0.75 | ALDH1A1 (0.35) | ERN1ALDH1A1SMN1; SMN2SRCTSHR | |
| SCHEMBL28221684 | 0.73 | ALDH1A1 (0.41) | ERN1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1312151 | 0.73 | ERN1 (0.56) | ERN1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18966864 | 0.73 | KMT2A (0.40) | ALDH1A1KMT2AKDM4ETSHRHRH3 | |
| SCHEMBL14877416 | 0.73 | ERN1 (0.56) | ERN1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29818729 | 0.72 | ALDH1A1 (0.36) | ERN1ALDH1A1SMN1; SMN2KDM4ESRC | |
| SCHEMBL686293 | 0.71 | ERN1 (0.54) | ERN1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9712548 | 0.71 | SRC (0.42) | ALDH1A1SMN1; SMN2KDM4EMAPTSRC | |
| SCHEMBL5530294 | 0.71 | ALDH1A1 (0.56) | ERN1ALDH1A1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572927-B2 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | DDT, OXER1, OSTC | ERN1 4262/4885ALDH1A1 1259/4885KMT2A 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.