Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19413331 | 0.81 | QPCT (0.51) | QPCTQPCTLCYP2D6HRH4HRH3 | |
| SCHEMBL13743314 | 0.79 | CYP3A4 (0.52) | QPCTQPCTLCYP2D6HRH4HRH3 | |
| SCHEMBL16136337 | 0.78 | QPCT (0.70) | QPCTQPCTLCYP2D6HRH4HRH3 | |
| SCHEMBL17481129 | 0.76 | QPCT (0.66) | QPCTQPCTLCYP2D6HRH4HRH3 | |
| SCHEMBL20417155 | 0.75 | QPCT (0.46) | QPCTQPCTLHRH4HRH3CYP3A4 | |
| SCHEMBL18381403 | 0.74 | TBXAS1 (0.57) | QPCTQPCTLCYP2D6HRH4CYP3A4 | |
| SCHEMBL19169449 | 0.72 | HPGD (0.57) | HPGDCYP3A4ALDH1A1CYP2C19MAPT | |
| SCHEMBL20625835 | 0.71 | HRH3 (0.44) | QPCTQPCTLHRH4HRH3 | |
| SCHEMBL19413330 | 0.71 | HRH3 (0.44) | QPCTQPCTLHRH4HRH3 | |
| SCHEMBL13781505 | 0.69 | HPGD (0.66) | HPGDALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576098-B2 | Heterocyclic compounds as inhibitors of factor VIIa | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-18 | — | — | US | disclosed |