Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13714619 | 0.92 | KIT (0.49) | KITBRAF | |
| SCHEMBL3866092 | 0.90 | KIT (0.50) | KITBRAF | |
| SCHEMBL13714564 | 0.89 | KIT (0.49) | KITBRAF | |
| SCHEMBL13714621 | 0.88 | KIT (0.47) | KITBRAF | |
| SCHEMBL13714592 | 0.87 | KIT (0.50) | KITBRAF | |
| SCHEMBL13714601 | 0.87 | KIT (0.48) | KITBRAF | |
| SCHEMBL13714533 | 0.87 | KIT (0.47) | KITBRAF | |
| SCHEMBL5675460 | 0.86 | KIT (0.47) | KITBRAF | |
| SCHEMBL5178265 | 0.86 | KIT (0.47) | KITBRAF | |
| SCHEMBL13714590 | 0.85 | KIT (0.48) | KITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572794-B2 | 4-hydroxy-4-methyl-piperidine-1 -carboxylic acid (4-{[2-(2-methyl-2H-indazol-6-ylcarbamoyl)-phenylamino]-methyl}-pyridin-2-yl)-amide; 2,6-dimethyl-morpholine-4-carboxylic acid (4-{[2-(1-methyl-1H-indazol-6-ylcarbamoyl)-phenylamino]-methyl}-pyridin-2-yl)-amide | BAYER SCHERING PHARMA AG (DE) | 2009-08-11 | — | — | US | disclosed |
| US-7572794-B2 | 4-hydroxy-4-methyl-piperidine-1 -carboxylic acid (4-{[2-(2-methyl-2H-indazol-6-ylcarbamoyl)-phenylamino]-methyl}-pyridin-2-yl)-amide; 2,6-dimethyl-morpholine-4-carboxylic acid (4-{[2-(1-methyl-1H-indazol-6-ylcarbamoyl)-phenylamino]-methyl}-pyridin-2-yl)-amide | BAYER SCHERING PHARMA AG (DE) | 2009-08-11 | — | — | US | disclosed |