Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 19/20 | 0.47 |
| ▸ | BRAF | P15056 | 19/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13714564 | 0.93 | KIT (0.49) | KITBRAFBRD4CREBBP | |
| SCHEMBL13714592 | 0.90 | KIT (0.50) | KITBRAF | |
| SCHEMBL13714601 | 0.90 | KIT (0.48) | KITBRAFBRD4CREBBP | |
| SCHEMBL13714619 | 0.89 | KIT (0.49) | KITBRAFBRD4CREBBP | |
| SCHEMBL13714621 | 0.89 | KIT (0.47) | KITBRAFBRD4CREBBP | |
| SCHEMBL13714533 | 0.89 | KIT (0.47) | KITBRAFBRD4CREBBP | |
| SCHEMBL5675460 | 0.88 | KIT (0.47) | KITBRAFBRD4CREBBP | |
| SCHEMBL3866092 | 0.86 | KIT (0.50) | KITBRAF | |
| SCHEMBL13714590 | 0.86 | KIT (0.48) | KITBRAFBRD4CREBBP | |
| SCHEMBL13714532 | 0.86 | KIT (0.48) | KITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807415-A2 | NOVEL ANTHRANILAMIDE PYRIDINUREAS AS VEGF RECEPTOR KINASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-07-18 | — | — | EP | claimed |
| WO-2006048248-A2 | NOVEL ANTHRANILAMIDE PYRIDINUREAS AS VEGF RECEPTOR KINASE IMHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-05-11 | — | — | WO | claimed |