Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13579042 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL13743171 | 0.71 | HSD17B10 (0.45) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL3860803 | 0.70 | CYP3A4 (0.47) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL3074458 | 0.69 | HSD17B10 (1.00) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL27733015 | 0.69 | KDM4E (0.65) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL2587900 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL12973890 | 0.68 | MEN1 (0.53) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL498897 | 0.68 | KDM4E (1.00) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL10535958 | 0.67 | NPC1 (0.56) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL3059145 | 0.67 | NPC1 (0.56) | KDM4EALDH1A1MAPTHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569596-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-08-04 | — | — | US | disclosed |
| US-7569596-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-08-04 | — | — | US | disclosed |
| US-7462723-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-12-09 | — | — | US | disclosed |
| US-7462723-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-12-09 | — | — | US | disclosed |