Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18086141 | 0.84 | GPR3 (0.44) | MAOAMAOBMAPTKDM4EATM | |
| SCHEMBL13715325 | 0.83 | KDM4E (0.48) | MAOAMAPTHTTKDM4EATM | |
| SCHEMBL30692086 | 0.83 | KDM4E (0.48) | MAOAMAPTHTTKDM4EATM | |
| SCHEMBL29397828 | 0.83 | KDM4E (0.52) | MAOAMAOBMAPTKDM4EATM | |
| SCHEMBL29398379 | 0.83 | KDM4E (0.52) | MAOAMAOBMAPTKDM4EATM | |
| SCHEMBL126273 | 0.83 | KDM4E (0.52) | MAOAMAOBMAPTKDM4EATM | |
| SCHEMBL15275604 | 0.83 | KDM4E (0.40) | MAOAMAOBKDM4EATML3MBTL1 | |
| SCHEMBL20706657 | 0.83 | GPR3 (0.40) | MAOAMAOBMAPTKDM4EATM | |
| SCHEMBL12926106 | 0.83 | KDM4E (0.40) | MAOAMAOBKDM4EATML3MBTL1 | |
| SCHEMBL16484421 | 0.82 | KDM4E (0.39) | MAPTKDM4EATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362463-B2 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362463-B2 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | SLC25A11, TIMM9, TIMM50 | MAOA 4023/4885MAOB 4280/4885MAPT 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.