⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62712 | 1.00 | — | — | |
| SCHEMBL2108448 | 1.00 | — | — | |
| SCHEMBL8579642 | 1.00 | TSHR (0.33) | — | |
| Hydrochloric Acid SCHEMBL5031695 | 0.96 | — | — | |
| Isopropyl Alcohol SCHEMBL10778246 | 0.83 | — | — | |
| Sulfuric Acid SCHEMBL15349351 | 0.83 | CA5A (0.38) | — | |
| Vinyl Ether SCHEMBL4968997 | 0.78 | TSHR (0.35) | — | |
| Vinyl Ether SCHEMBL4968989 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL16859445 | 0.78 | — | — | |
| SCHEMBL16859446 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598921-A1 | MACROCYCLIC KRAS INHIBITORS AND METHODS OF USE | Amgen Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250236631-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2025-07-24 | — | — | US | disclosed |
| US-20240294551-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2024-09-05 | — | — | US | disclosed |
| WO-2024107686-A1 | MACROCYCLIC KRAS INHIBITORS AND METHODS OF USE | AMGEN INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| US-8986400-B2 | Fuels and fuel additives production from glycerol conversion using a monohydric alcohol and heterogeneous catalysis | SOUTHWEST RESEARCH INSTITUTE (US) | 2015-03-24 | — | — | US | disclosed |
| US-8986400-B2 | Fuels and fuel additives production from glycerol conversion using a monohydric alcohol and heterogeneous catalysis | SOUTHWEST RESEARCH INSTITUTE (US) | 2015-03-24 | — | — | US | disclosed |
| US-8791102-B2 | Acetanilide sphingosine-1-phosphate receptor antagonists | EXELIXIS, INC. (US) | 2014-07-29 | — | — | US | disclosed |
| US-20140101988-A1 | Fuels And Fuel Additives Production From Glycerol Conversion Using A Monohydric Alcohol And Heterogeneous Catalysis | SOUTHWEST RESEARCH INSTITUTE (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140101988-A1 | Fuels And Fuel Additives Production From Glycerol Conversion Using A Monohydric Alcohol And Heterogeneous Catalysis | SOUTHWEST RESEARCH INSTITUTE (US) | 2014-04-17 | — | — | US | disclosed |
| WO-2013113117-A1 | FLUORINATED PHOSPHONIUM IONIC SALTS LINKED TO CARBENE-PRECURSORS | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2013-08-08 | — | — | WO | disclosed |
| US-20070072967-A1 | Polymeric molding compositions based on thermoplastic polyamides | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH | 2007-03-29 | — | — | US | disclosed |
| US-7189504-B2 | Compositions and methods for detecting and quantifying COX-2 activity and 2-arachidonylglycerol metabolites | VANDERBILT UNIVERSITY (US) | 2007-03-13 | — | — | US | disclosed |
| US-7049344-B2 | Highly selective inhibitors of the urokinase plasminogen activator | WILEX BIOTECHNOLOGY GMBH (DE) | 2006-05-23 | — | — | US | disclosed |
| US-20050209173-A1 | Neurodegenerative protein aggregation inhibition methods and compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-09-22 | — | — | US | disclosed |
| US-20050119348-A1 | Highly selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2005-06-02 | — | — | US | disclosed |
| WO-2005011610-A2 | NEURODEGENERATIVE PROTEIN AGGREGATION INHIBITION METHODS AND COMPOUNDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2005-02-10 | — | — | WO | disclosed |
| US-6841702-B2 | Highly selective inhibitors of the urokinase plasminogen activator | WILEX BIOTECHNOLOGY GMBH (DE) | 2005-01-11 | — | — | US | disclosed |
| US-20030100584-A1 | Highly selective inhibitors of the urokinase plasminogen activator | WILEX AG (DE) | 2003-05-29 | — | — | US | disclosed |
| EP-0767776-A1 | OLIGOMER LIQUID CRYSTAL TRIPHENYLENE DERIVATIVES AND THEIR USE AS CHARGE CARRYING SUBSTANCES IN ELECTROPHOTOGRAPHY | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000208-A1 | OLIGOMER LIQUID CRYSTAL TRIPHENYLENE DERIVATIVES AND THEIR USE AS CHARGE CARRYING SUBSTANCES IN ELECTROPHOTOGRAPHY | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-04 | — | — | WO | disclosed |