⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16243333 | 0.85 | RXFP1 (0.41) | — | |
| SCHEMBL16243369 | 0.84 | PDE4A (0.40) | — | |
| SCHEMBL13715903 | 0.80 | — | — | |
| SCHEMBL3952638 | 0.77 | PDE4A (0.40) | — | |
| SCHEMBL19981005 | 0.76 | PDE4A (0.39) | — | |
| SCHEMBL15892161 | 0.76 | PDE4A (0.39) | — | |
| SCHEMBL15850630 | 0.76 | PDE4A (0.39) | — | |
| SCHEMBL5505121 | 0.75 | RXFP1 (0.43) | — | |
| SCHEMBL2404929 | 0.75 | RXFP1 (0.44) | — | |
| SCHEMBL16242977 | 0.75 | RXFP1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569685-B2 | Artificial RNAóS modified at the 2ó-hydroxyl group | JAPAN SCIENCCE AND TECHNOLOGY AGENCY (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20080021206-A1 | Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-01-24 | — | — | US | disclosed |