Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.41 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.39 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.39 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505121 | 0.91 | RXFP1 (0.43) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL2404929 | 0.91 | RXFP1 (0.44) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL16243333 | 0.89 | RXFP1 (0.41) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL12212793 | 0.86 | ADORA3 (0.44) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL2522409 | 0.86 | ADORA3 (0.44) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL26882824 | 0.85 | STING1 (0.45) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL14946326 | 0.84 | STING1 (0.46) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL23813544 | 0.83 | STING1 (0.56) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL6895355 | 0.83 | STING1 (0.56) | RXFP1STING1LMNAKMT2ARAPGEF3 | |
| SCHEMBL22983991 | 0.83 | STING1 (0.56) | RXFP1STING1LMNAKMT2ARAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350080-A1 | INHIBITION OF VIRAL GENE EXPRESSION | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2014-11-27 | — | — | US | disclosed |