Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270878 | 0.90 | PTPN1 (0.46) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL23451959 | 0.77 | KDM4E (0.57) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL612007 | 0.76 | MAPT (0.56) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14947250 | 0.74 | POLB (0.58) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL23452163 | 0.74 | KDM4E (0.54) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL12464636 | 0.73 | MAPT (0.37) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL12357238 | 0.72 | KDM4E (0.49) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL2879066 | 0.72 | KDM4E (0.60) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL12357351 | 0.71 | PTPN1 (0.61) | MAPTPOLBMEN1KMT2ACRHBP | |
| SCHEMBL2157496 | 0.71 | MAPT (0.76) | MAPTKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | disclosed |