Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13715912 | 0.90 | MAPT (0.50) | MAOAMAOBALDH1A1TP53HPGD | |
| SCHEMBL12357351 | 0.82 | PTPN1 (0.61) | PTPN1PTPRFIKBKBPTPRAKMT2A | |
| SCHEMBL27610463 | 0.81 | PTPN1 (0.59) | PTPN1PTPRFIKBKBPTPRAKMT2A | |
| SCHEMBL3811053 | 0.80 | PTPN1 (0.48) | PTPN1PTPRFIKBKBPTPRAALDH1A1 | |
| SCHEMBL614118 | 0.74 | CDC7 (0.54) | PTPN1PTPRFIKBKBPTPRAKMT2A | |
| SCHEMBL12922055 | 0.71 | IKBKB (0.54) | PTPN1PTPRFIKBKBHDAC2ALDH1A1 | |
| SCHEMBL2157963 | 0.71 | IKBKB (0.54) | PTPN1PTPRFIKBKBPTPRAALDH1A1 | |
| SCHEMBL2157913 | 0.70 | ALDH1A1 (0.47) | PTPN1PTPRFALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL16425579 | 0.69 | RAB9A (0.59) | SMN1; SMN2TP53HPGDKMT2AMEN1 | |
| SCHEMBL12464634 | 0.69 | PSMB5 (0.38) | ALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206709-A2 | Thiophene derivatives as antiviral agents for flavivirus infection | Virochem Pharma Inc. (CA) | 2010-07-14 | — | — | EP | disclosed |
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | disclosed |