SCHEMBL1371681

SCHEMBL1371681

CCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@](C)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O)c1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 1/20 0.52
▸ MC5R P33032 1/20 0.52
▸ MC3R P41968 1/20 0.52
▸ MC1R Q01726 1/20 0.52
▸ IL23R Q5VWK5 3/20 0.52
▸ C5AR1 P21730 1/20 0.51
▸ KISS1R Q969F8 5/20 0.50
▸ CCKBR P32239 2/20 0.49
▸ GLP1R P43220 7/20 0.49
▸ GIPR P48546 6/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580537 0.88 KISS1R (0.63) IL23RC5AR1KISS1RGLP1R
SCHEMBL29580972 0.88 KISS1R (0.63) IL23RC5AR1KISS1RGLP1R
SCHEMBL29581575 0.87 MC4R (0.60) MC4RMC5RMC3RMC1RIL23R
SCHEMBL29580601 0.81 CALCRL (0.57) —
SCHEMBL29581453 0.81 CALCRL (0.57) —
SCHEMBL31488939 0.80 KISS1R (0.63) MC4RMC5RMC3RMC1RIL23R
SCHEMBL30598997 0.78 IL23R (0.62) MC4RMC5RMC3RMC1RIL23R
SCHEMBL30750450 0.78 MC4R (0.71) MC4RMC5RMC3RMC1RIL23R
SCHEMBL31489038 0.77 KISS1R (0.60) IL23RC5AR1KISS1R
SCHEMBL31182780 0.77 C5AR1 (0.66) MC4RMC5RMC3RMC1RC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC (CA) 2016-09-15 — — US disclosed
EP-2794663-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2014-10-29 — — EP disclosed
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-11-24 — — US disclosed
WO-2010063124-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2010-06-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 MC4R 946/4885MC5R 2580/4885MC3R 1886/4885
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 MC4R 946/4885MC5R 2580/4885MC3R 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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