Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14508383 | 0.88 | TSHR (0.65) | TSHRHSD17B10NPSR1HDAC8HDAC6 | |
| SCHEMBL13718432 | 0.81 | TSHR (0.74) | TSHRHSD17B10NPSR1HDAC8HDAC6 | |
| SCHEMBL28328422 | 0.79 | TSHR (0.72) | TSHRHSD17B10HDAC8HDAC6HTT | |
| SCHEMBL5620857 | 0.77 | PPIA (0.76) | TSHRHDAC8HDAC6CA1KMT2A | |
| SCHEMBL14454229 | 0.76 | TSHR (0.62) | TSHRHSD17B10HDAC8HDAC6HDAC3 | |
| SCHEMBL45806 | 0.76 | TSHR (0.66) | TSHRHSD17B10NPSR1HDAC8HDAC6 | |
| SCHEMBL22482890 | 0.75 | TSHR (0.68) | TSHRHSD17B10NPSR1HDAC8HDAC6 | |
| SCHEMBL21206391 | 0.75 | TSHR (0.60) | TSHRHDAC8HDAC6CA2KMT2A | |
| SCHEMBL2240872 | 0.74 | PPIA (0.61) | TSHRHSD17B10HDAC8HDAC6CA1 | |
| SCHEMBL7183285 | 0.74 | KMT2A (0.71) | TSHRHDAC8HDAC6KMT2AHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089988-B1 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1044364-B1 | METHOD FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | AVENTIS PHARM PROD INC (US) | 2007-06-13 | — | — | EP | disclosed |