Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.74 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516468 | 0.92 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL3979207 | 0.91 | TLR7 (0.82) | TLR7TLR8 | |
| SCHEMBL13721794 | 0.89 | TLR7 (0.59) | TLR7TLR8 | |
| SCHEMBL14516464 | 0.87 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL18429392 | 0.86 | TLR7 (0.86) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL483385 | 0.85 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL18680036 | 0.85 | TLR7 (0.85) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL29371102 | 0.85 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL3970939 | 0.84 | TLR7 (0.70) | TLR7TLR8 | |
| SCHEMBL13722028 | 0.83 | TLR7 (0.82) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642580-B1 | Sulfonamide substituted imidazoquinolines | COLEY PHARM GROUP INC (US) | 2009-08-19 | — | — | EP | disclosed |