Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.86 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18680036 | 0.99 | TLR7 (0.85) | TLR7TLR8 | |
| SCHEMBL13722028 | 0.93 | TLR7 (0.82) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL483385 | 0.93 | TLR7 (1.00) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL29371102 | 0.93 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL25636046 | 0.92 | TLR7 (0.80) | TLR7TLR8 | |
| SCHEMBL3979207 | 0.91 | TLR7 (0.82) | TLR7TLR8 | |
| SCHEMBL23554228 | 0.90 | TLR7 (0.78) | TLR7TLR8 | |
| SCHEMBL18429237 | 0.90 | TLR7 (0.80) | TLR7TLR8 | |
| SCHEMBL29182347 | 0.90 | TLR7 (0.94) | TLR7TLR8 | |
| SCHEMBL18680037 | 0.89 | TLR7 (0.79) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556167-B2 | TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs) | YALE UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |