Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279524 | 0.98 | SIGMAR1 (0.51) | SIGMAR1DHFRL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL12047901 | 0.95 | SIGMAR1 (0.51) | SIGMAR1DHFRL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL12048286 | 0.93 | SIGMAR1 (0.48) | SIGMAR1DHFRL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL12047767 | 0.93 | SIGMAR1 (0.50) | SIGMAR1DHFRL3MBTL1PDE5A | |
| SCHEMBL12048291 | 0.92 | SIGMAR1 (0.47) | SIGMAR1DHFRL3MBTL1PDE5A | |
| SCHEMBL12047773 | 0.92 | SIGMAR1 (0.47) | SIGMAR1DHFRL3MBTL1PDE5A | |
| SCHEMBL12047792 | 0.92 | SIGMAR1 (0.47) | SIGMAR1DHFRL3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL12047986 | 0.92 | SIGMAR1 (0.47) | SIGMAR1DHFRL3MBTL1PDE5A | |
| SCHEMBL12048463 | 0.92 | SIGMAR1 (0.47) | SIGMAR1DHFRL3MBTL1PDE5A | |
| SCHEMBL279223 | 0.91 | SIGMAR1 (0.51) | SIGMAR1DHFRL3MBTL1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576484-B2 | Organic electroluminescence device | LG DISPLAY CO., LTD. (KR) | 2009-08-18 | — | — | US | disclosed |