SCHEMBL13722372

SCHEMBL13722372

CCNC(=O)Nc1ccc(-c2sc3c(c2CN(C)Cc2ccccn2)c(=O)n(-c2ccccc2)c(=O)n3Cc2c(F)cccc2F)cc1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13722045 0.96 GNRHR (0.79) GNRHR
SCHEMBL13722091 0.93 GNRHR (0.76) GNRHR
SCHEMBL779746 0.92 GNRHR (1.00) GNRHR
SCHEMBL1642713 0.92 GNRHR (1.00) GNRHR
SCHEMBL13722075 0.91 GNRHR (0.84) GNRHR
Hydrochloric Acid SCHEMBL1644350 0.91 GNRHR (0.99) GNRHR
SCHEMBL13721934 0.91 GNRHR (0.73) GNRHR
SCHEMBL4056437 0.90 GNRHR (0.87) GNRHR
SCHEMBL4052003 0.90 GNRHR (0.85) GNRHR
SCHEMBL6646847 0.90 GNRHR (0.85) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569570-B2 Thienopyrimidines, process for preparing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-08-04 US disclosed
US-7569570-B2 Thienopyrimidines, process for preparing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-08-04 US disclosed