Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13146956 | 0.92 | MC4R (0.52) | QPCTMAPTMC4R | |
| SCHEMBL13724368 | 0.92 | QPCT (0.44) | QPCTMAPTMC4RALDH1A1PKM | |
| SCHEMBL13147602 | 0.83 | MC4R (0.49) | QPCTMC4R | |
| SCHEMBL13146920 | 0.83 | MC4R (0.49) | QPCTMC4R | |
| SCHEMBL13146943 | 0.82 | MC4R (0.53) | QPCTMC4R | |
| SCHEMBL13723953 | 0.80 | MC4R (0.42) | MC4R | |
| SCHEMBL3822838 | 0.77 | MC4R (0.60) | QPCTMC4R | |
| SCHEMBL3076845 | 0.77 | MC4R (0.54) | MC4R | |
| SCHEMBL3076843 | 0.77 | MC4R (0.54) | MC4R | |
| SCHEMBL3096173 | 0.76 | MC4R (0.59) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |