Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 13/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13146950 | 0.92 | MC4R (0.51) | MC4R | |
| SCHEMBL13146931 | 0.83 | MC4R (0.53) | MC4R | |
| SCHEMBL13724565 | 0.83 | MC4R (0.43) | MC4REEDTLR9TLR8TLR7 | |
| SCHEMBL13723410 | 0.80 | QPCT (0.45) | MC4R | |
| SCHEMBL3095698 | 0.78 | MC4R (0.56) | MC4R | |
| SCHEMBL3825823 | 0.78 | MC4R (0.61) | MC4R | |
| SCHEMBL3095694 | 0.78 | MC4R (0.56) | MC4R | |
| SCHEMBL3819568 | 0.77 | MC4R (0.59) | MC4R | |
| SCHEMBL13146951 | 0.77 | MC4R (0.49) | MC4R | |
| SCHEMBL14193825 | 0.74 | MC4R (0.58) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |