Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 12/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093411 | 0.87 | MC4R (0.72) | MC4RPOLBKDM4E | |
| SCHEMBL13147440 | 0.77 | MC4R (0.59) | MC4RPOLBKMT2A | |
| SCHEMBL3093429 | 0.75 | MC4R (0.54) | MC4RHPGDKMT2A | |
| SCHEMBL13147437 | 0.73 | MC4R (0.72) | MC4RPOLB | |
| SCHEMBL3095690 | 0.73 | KDM4E (0.48) | MC4RKDM4EALDH1A1KMT2A | |
| SCHEMBL13147484 | 0.71 | MC4R (0.56) | MC4RPOLBKMT2A | |
| SCHEMBL3093419 | 0.71 | MC4R (0.69) | MC4RKDM4E | |
| SCHEMBL14223731 | 0.71 | MC4R (0.55) | MC4RPOLBKMT2A | |
| SCHEMBL3080769 | 0.71 | ALDH1A1 (0.52) | MC4RHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL13147476 | 0.70 | MC4R (0.62) | MC4RPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |