Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.52 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090264 | 0.86 | MC4R (0.52) | MC4RMEN1KMT2APOLBMAPT | |
| SCHEMBL13724467 | 0.77 | MAPK8 (0.43) | MAPK8SLC13A5MC4RKMT2AL3MBTL1 | |
| SCHEMBL30873972 | 0.73 | SLC13A5 (0.62) | SLC13A5POLBHSD17B10TSHR | |
| SCHEMBL1209727 | 0.73 | SLC13A5 (0.62) | SLC13A5POLBHSD17B10TSHR | |
| SCHEMBL30100430 | 0.72 | CSNK2A1 (0.59) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL91954 | 0.72 | CSNK2A1 (0.59) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL10836064 | 0.71 | SLC13A5 (0.59) | SLC13A5POLBALDH1A1HSD17B10TSHR | |
| SCHEMBL7839891 | 0.70 | FFAR4 (0.48) | SLC13A5ALDH1A1L3MBTL1 | |
| SCHEMBL13205866 | 0.70 | HSD17B10 (0.70) | MAPK8SLC13A5MAPTTDP1ALDH1A1 | |
| SCHEMBL29773177 | 0.70 | HSD17B10 (0.70) | MAPK8SLC13A5MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |