Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | HCN1 | O60741 | 1/20 | 0.37 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827523 | 0.90 | MC4R (0.53) | MC4RSIGMAR1SMN1; SMN2KMT2A | |
| SCHEMBL13723976 | 0.77 | MAPK8 (0.52) | MAPK8MC4RKMT2AL3MBTL1SLC13A5 | |
| SCHEMBL3085659 | 0.74 | MC4R (0.55) | MC4RSMN1; SMN2KMT2A | |
| SCHEMBL13724393 | 0.74 | MC4R (0.44) | MAPK8MC4RSMN1; SMN2KMT2A | |
| SCHEMBL3089406 | 0.71 | MC4R (0.49) | MC4RFPR3 | |
| SCHEMBL3086877 | 0.71 | MC4R (0.50) | MC4RFPR3 | |
| SCHEMBL3084384 | 0.70 | MC4R (0.52) | MC4RSMN1; SMN2KMT2A | |
| SCHEMBL3082690 | 0.69 | L3MBTL1 (0.49) | MC4RSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL3089926 | 0.69 | MC4R (0.57) | MC4RSMN1; SMN2L3MBTL1 | |
| SCHEMBL3080666 | 0.69 | DRD2 (0.59) | MC4RSIGMAR1DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |