Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 18/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095805 | 0.91 | MC4R (0.63) | MC4R | |
| SCHEMBL3092179 | 0.80 | MC4R (0.49) | MC4RMAPK1MEN1HTTKMT2A | |
| SCHEMBL3095811 | 0.77 | MC4R (0.58) | MC4RMAPK1 | |
| SCHEMBL3089431 | 0.70 | MC4R (0.71) | MC4R | |
| SCHEMBL13147367 | 0.69 | MC4R (0.73) | MC4R | |
| SCHEMBL13725150 | 0.69 | MC4R (0.67) | MC4R | |
| SCHEMBL14193791 | 0.69 | MC4R (0.72) | MC4R | |
| SCHEMBL13725172 | 0.68 | MC4R (0.50) | MC4RMEN1HTTKMT2A | |
| SCHEMBL3090271 | 0.68 | MC4R (0.72) | MC4R | |
| SCHEMBL3089440 | 0.68 | MC4R (1.00) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |