Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724296 | 0.84 | MC4R (0.52) | MC4RKCNH2LMNAHTTPARP10 | |
| SCHEMBL3089391 | 0.84 | MC4R (0.67) | MC4RKCNH2 | |
| SCHEMBL3083746 | 0.74 | MC4R (0.62) | MC4RKCNH2 | |
| SCHEMBL13724049 | 0.74 | MC4R (0.48) | MC4RKCNH2MEN1KMT2A | |
| SCHEMBL13725150 | 0.73 | MC4R (0.67) | MC4R | |
| SCHEMBL13723841 | 0.73 | MC4R (0.47) | MC4RKCNH2MEN1KMT2A | |
| SCHEMBL3084125 | 0.73 | MC4R (0.61) | MC4RKCNH2 | |
| SCHEMBL6222542 | 0.72 | MC4R (0.64) | MC4RKCNH2 | |
| SCHEMBL13725053 | 0.70 | MC4R (0.78) | MC4RKCNH2LMNA | |
| SCHEMBL21439307 | 0.69 | MAPK8 (0.44) | MC4RKCNH2LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |