Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027065 | 0.89 | MC4R (0.73) | MC4RKCNH2LMNAHPGD | |
| SCHEMBL4062778 | 0.88 | MC4R (0.72) | MC4RKCNH2LMNAHPGD | |
| SCHEMBL3089391 | 0.86 | MC4R (0.67) | MC4RKCNH2 | |
| SCHEMBL4818014 | 0.85 | MC4R (0.59) | MC4RKCNH2 | |
| SCHEMBL4071069 | 0.84 | MC4R (0.66) | MC4RKCNH2LMNAHPGD | |
| SCHEMBL4817989 | 0.84 | MC4R (0.66) | MC4RKCNH2LMNAHPGD | |
| SCHEMBL14027063 | 0.81 | MC4R (0.61) | MC4RKCNH2LMNAHPGD | |
| SCHEMBL4071043 | 0.80 | MC4R (0.61) | MC4RKCNH2LMNAHPGD | |
| SCHEMBL4825297 | 0.80 | MC4R (0.61) | MC4RKCNH2LMNAHPGD | |
| SCHEMBL4360481 | 0.80 | MC4R (0.67) | MC4RKCNH2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |