Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 15/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13725053 | 0.85 | MC4R (0.78) | MC4RKCNH2 | |
| SCHEMBL3089391 | 0.83 | MC4R (0.67) | MC4RKCNH2 | |
| SCHEMBL4071046 | 0.82 | MC4R (0.47) | MC4RKCNH2 | |
| SCHEMBL14027065 | 0.75 | MC4R (0.73) | MC4RKCNH2 | |
| SCHEMBL4062778 | 0.74 | MC4R (0.72) | MC4RKCNH2 | |
| SCHEMBL3084125 | 0.74 | MC4R (0.61) | MC4RKCNH2 | |
| SCHEMBL3083746 | 0.73 | MC4R (0.62) | MC4RKCNH2 | |
| SCHEMBL6222542 | 0.72 | MC4R (0.64) | MC4RKCNH2 | |
| SCHEMBL6745160 | 0.70 | ALDH1A1 (0.54) | MC4RKCNH2 | |
| SCHEMBL13724296 | 0.70 | MC4R (0.52) | MC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |