Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | HCK | P08631 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954886 | 0.73 | CCNT1 (0.39) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL2549215 | 0.73 | CCNT1 (0.39) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL29953488 | 0.71 | CCNT1 (0.38) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL29956035 | 0.71 | CCNT1 (0.38) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL16044258 | 0.71 | CYP2A6 (0.51) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL29957318 | 0.71 | PARP1 (0.40) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL29954872 | 0.71 | GABRP (0.41) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL2619212 | 0.71 | PIM1 (0.34) | — | |
| SCHEMBL28103741 | 0.71 | GRM4 (0.36) | TDO2 | |
| SCHEMBL4067918 | 0.71 | MAPK1 (0.41) | CCNT1CDK9HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150866-A1 | PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | INDUSTRIAL RESEARCH LIMITED (NZ) | 2012-11-08 | — | — | WO | disclosed |