Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13726535 | 1.00 | MEN1 (0.48) | MEN1KMT2ANAAALMNASIGMAR1 | |
| SCHEMBL12744494 | 0.90 | MEN1 (0.56) | MEN1KMT2ANAAALMNASIGMAR1 | |
| SCHEMBL10601401 | 0.85 | NPSR1 (0.36) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL6883913 | 0.82 | NPSR1 (0.35) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL6883918 | 0.82 | NPSR1 (0.35) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL30102464 | 0.82 | LMNA (0.48) | MEN1KMT2ANAAALMNASIGMAR1 | |
| SCHEMBL3085373 | 0.79 | NPSR1 (0.40) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL16297578 | 0.75 | — | — | |
| SCHEMBL16594103 | 0.74 | MEN1 (0.46) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL16594107 | 0.74 | MEN1 (0.46) | MEN1KMT2APRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149639-A1 | NOVEL LATE TRANSITION METAL CATALYSTS FOR SELECTIVE POLYMER FORMATION | RYERSON UNIVERSITY (CA) | 2012-11-08 | — | — | WO | disclosed |