Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | GABRP | O00591 | 4/20 | 0.39 |
| ▸ | GABRD | O14764 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.39 |
| ▸ | GABRE | P78334 | 4/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13726065 | 0.93 | AR (0.39) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13718464 | 0.90 | AR (0.42) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13726909 | 0.89 | TAAR1 (0.43) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13726276 | 0.88 | AR (0.46) | AR | |
| SCHEMBL13717494 | 0.88 | AR (0.40) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13726082 | 0.88 | AR (0.40) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13726158 | 0.87 | AR (0.47) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8472 | 0.85 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23425394 | 0.85 | AR (0.42) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13725657 | 0.85 | AR (0.42) | ARGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705029-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | Rhizen Pharmaceuticals S.A. (CH) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012151525-A9 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012151525-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-11-08 | — | — | WO | disclosed |