Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730825 | 0.85 | PDE2A (0.44) | PDE2A | |
| SCHEMBL9616518 | 0.72 | GPR84 (0.47) | PDE2A | |
| SCHEMBL21985328 | 0.70 | PDE2A (0.72) | PDE2A | |
| SCHEMBL16868293 | 0.69 | PDE2A (1.00) | PDE2A | |
| SCHEMBL13727088 | 0.69 | PDE2A (0.65) | PDE2A | |
| SCHEMBL438172 | 0.68 | POLB (0.59) | — | |
| SCHEMBL3495651 | 0.68 | PDE5A (0.60) | — | |
| SCHEMBL7887063 | 0.68 | AR (0.49) | — | |
| SCHEMBL29195792 | 0.67 | AR (0.45) | — | |
| SCHEMBL3494121 | 0.67 | KMT2A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |