Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 10/20 | 0.64 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.64 |
| ▸ | MIF | P14174 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929320 | 0.91 | HIF1A (0.55) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL71034 | 0.91 | HIF1A (0.55) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL11044314 | 0.89 | P4HTM (0.53) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL28654391 | 0.89 | P4HTM (0.70) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28470042 | 0.89 | HIF1A (0.54) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL31512829 | 0.88 | P4HTM (0.52) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL1951045 | 0.88 | MAP4K4 (0.55) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL2636731 | 0.88 | P4HTM (0.57) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL4725410 | 0.88 | MAP4K4 (0.68) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL254682 | 0.88 | MAP4K4 (0.55) | P4HTMP4HA1MIFKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699561-B1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | ORION CORP (FI) | 2015-06-03 | — | — | EP | disclosed |
| US-8921378-B2 | Androgen receptor modulating carboxamides | ORION CORPORATION (FI) | 2014-12-30 | — | — | US | disclosed |
| EP-2699561-A1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | Orion Corporation (FI) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143599-A1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | ORION CORPORATION (FI) | 2012-10-26 | — | — | WO | disclosed |