Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.52 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731115 | 0.88 | P4HTM (0.64) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL1951045 | 0.85 | MAP4K4 (0.55) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL71034 | 0.84 | HIF1A (0.55) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL29929320 | 0.84 | HIF1A (0.55) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL7946346 | 0.84 | MAP4K4 (0.48) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL31359466 | 0.84 | P4HTM (0.59) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL249720 | 0.84 | P4HTM (0.59) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL28654391 | 0.82 | P4HTM (0.70) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| Hydrochloric Acid SCHEMBL28470042 | 0.82 | HIF1A (0.54) | MAP4K4HIF1AP4HTMP4HA1MIF | |
| SCHEMBL11044314 | 0.82 | P4HTM (0.53) | MAP4K4HIF1AP4HTMP4HA1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |